Congenital transmission of Trichinella spiralis in experimentally infected mice

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Expression of MyoD and myogenin in muscles of mice experimentally infected with Trichinella spiralis or Trichinella pseudospiralis.

We developed a detection system for myogenic regulatory factors such as MyoD and myogenin. Adapting the method we performed a longitudinal analysis of such regulatory factors after infection with T. spiralis and T. pseudospiralis. MyoD and myogenin were expressed from the early phase of cystogenesis in T. spiralis infection. The expression returned to the normal level after 18 days from the inf...

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Experimental Transmission of Trichinella spiralis to Swine by Infected Rats

The role of rats in the transmission of Trichinella spiralis to swine is controversial because some experimental investigations have failed to show that swine will eat rat carcasses. Confinement-reared, grain-fed hogs were offered fresh rat carcasses harboring varying densities of muscle larvae. In all trials, rat carcasses were readily eaten in part or in their entirety, usually within a few h...

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Modulation of particle uptake in Trichinella spiralis-infected mice.

Mice were infected with 170 Trichinella spiralis larvae, and their blood clearance of carbon particles was studied 4, 7, 13, 32, and 135 days later and compared with that of noninfected control mice. Clearance in mice with a 4-day-old infection was comparable to that in the controls; clearances in mice with 7- and 13-day-old infections were increasingly accelerated and significantly different f...

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Distribution of Trichinella spiralis larvae in selected muscles and organs of experimentally infected swine.

Thirty-two Hampshire-Yorkshire pigs (6 to 8 wk old) were inoculated with the Beltsville strain of Trichinella spiralis at a level of about 880 larvae/kg of body weight (about 15 kg). At about 100 kg, the pigs were slaughtered and 10-g samples of muscle and other tissues were digested in pepsin-HC1 and examined microscopically for T. spiralis larvae. The mean number of larvae recovered/gram was:...

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Infectivity, reproductive capacity and distribution of Trichinella spiralis and T. pseudospiralis larvae in experimentally infected sheep.

Twelve Merino sheep were experimentally shown to be susceptible to infection with Trichinella spiralis or T. pseudospiralis by feeding on infected carcasses of mice or by oral intubation with recovered muscle larvae. The larvae recovered from the sheep showed variable tissue distribution. The diaphragm and tongue were most affected. The viability of the recovered larvae was confirmed by success...

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ژورنال

عنوان ژورنال: Helminthologia

سال: 2006

ISSN: 1336-9083,0440-6605

DOI: 10.2478/s11687-006-0002-4